R. de Vlaming May 4, 2021

Welcome to the homepage of Ronald de Vlaming, Assistant Professor at the Depart of Economics, School of Business and Economics, Vrij Universiteit Amsterdam, affiliated with the Erasmus University Rotterdam Institute for Behavior and Biology (EURIBEB), member of the Social Science Genetic Association Consortium (SSGAC).

Efficient Multivariate GREML

R. de Vlaming October 12, 2021

Researchers from the Vrije Universiteit Amsterdam, Erasmus University Rotterdam, University of Cambridge, McGill University, and University of Wisconsin-Madison have developed a new tool for joint, efficient estimation of large genetic correlation matrices. This command-line tool, called MGREML, is available on GitHub. The manuscript in which MGREML is described and applied to 74 brain measures and several behavioural traits has been published in Communications Biology.

Joint Approximate Diagonalization

R. de Vlaming October 8, 2021

Researchers from the Vrije Universiteit Amsterdam and the University of Cambridge have developed JADOC: a new method for joint approximate diagonalization of multiple positive (semi)-definite matrices. This method is implemented as a tool for Python 3.x and is available on GitHub. The article in which JADOC is described is now available as preprint on arXiv

Signatures of negative selection

R. de Vlaming April 30, 2018

The Vrije Universiteit Amsterdam has posted a short news item (in Dutch) on its website about the recent publication in Nature Genetics on signatures of negative selection in the genetic architecture of human complex traits. An open-access version of the manuscript can be found here.

MetaGAP calculator

R. de Vlaming September 27, 2016

The MetaGAP calculator described in De Vlaming et al. (2016) can be accessed here or using the menu. Edit [4/30/18]: the manuscript on the MetaGAP calculator has now also been published in PLOS Genetics.