Welcome

R. de Vlaming March 10, 2023

Welcome to the homepage of Ronald de Vlaming, Assistant Professor at the Depart of Economics, School of Business and Economics, Vrij Universiteit Amsterdam, member of the Social Science Genetic Association Consortium (SSGAC).

Machine Learning Summer School

R. de Vlaming March 10, 2023

From July 3 until July 7, Lukas Hoesch and Ronald de Vlaming will teach a summer school on Foundations of Machine Learning with Applications in Python.

In this course, we provide a fast-paced and solution-oriented introduction to machine-learning algorithms. During the lectures, we will introduce you to a wide variety of machine-learning techniques, ranging from linear and nonlinear regression models to dimensionality-reduction techniques and clustering methods, as well as deep learning using neural networks. During the lab sessions, we will guide you step by step through real-life case studies in economics, business, and medicine.

The summer school is hosted by the Tinbergen Institute as part of the research master program in Business Data Science.

To find out more about this course and to apply, please visit the Summer School Website.

Mediation Analysis using GREML

R. de Vlaming February 21, 2023

Researchers from the Vrije Universiteit Amsterdam, Erasmus University Rotterdam, and University of Cambridge have developed a method for Mediation Analysis using GREML (MA-GREML). This method is able to quantify the degree to which the genetic variance of a given outcome is mediated by an intermediate trait. MA-GREML is incorporated in the MGREML tool, which is available on GitHub. The method and some applications have been published in PLOS Genetics.

Efficient Multivariate GREML

R. de Vlaming October 12, 2021

Researchers from the Vrije Universiteit Amsterdam, Erasmus University Rotterdam, University of Cambridge, McGill University, and University of Wisconsin-Madison have developed a new tool for joint, efficient estimation of large genetic correlation matrices. This command-line tool, called MGREML, is available on GitHub. The manuscript in which MGREML is described and applied to 74 brain measures and several behavioural traits has been published in Communications Biology.

Joint Approximate Diagonalization

R. de Vlaming October 8, 2021

Researchers from the Vrije Universiteit Amsterdam and the University of Cambridge have developed JADOC: a new method for joint approximate diagonalization of multiple positive (semi)-definite matrices. This method is implemented as a tool for Python 3.x and is available on GitHub. The article in which JADOC is described is now available as preprint on arXiv

Signatures of negative selection

R. de Vlaming April 30, 2018

The Vrije Universiteit Amsterdam has posted a short news item (in Dutch) on its website about the recent publication in Nature Genetics on signatures of negative selection in the genetic architecture of human complex traits. An open-access version of the manuscript can be found here.

MetaGAP calculator

R. de Vlaming September 27, 2016

The MetaGAP calculator described in De Vlaming et al. (2016) can be accessed here or using the menu. Edit [4/30/18]: the manuscript on the MetaGAP calculator has now also been published in PLOS Genetics.