Publications


Peer-reviewed

  • Signatures of negative selection in the genetic architecture of human complex traits. J. Zeng, R. de Vlaming, Y. Wu, M.R. Robinson, L.R. Lloyd-Jones, L. Yengo, C.X. Yap, A. Xue, J. Sidorenko, A.F. McRae, J.E. Powell, G.W. Montgomery, A. Metspalu, T. Esko, G. Gibson, N.R. Wray, P.M. Visscher, and J. Yang, 2018, Nature Genetics, 50, 746–753. doi:10.1038/s41588-018-0101-4
  • Hidden heritability due to heterogeneity across seven populations. F.C. Tropf, S.H. Lee, R.M. Verweij, G. Stulp, P.J. van der Most, R. de Vlaming, A. Bakshi, D.A. Briley, C. Rahal, R. Hellpap, A.N. Iliadou, T. Esko, A. Metspalu, S.E. Medland, N.G. Martin, N. Barban, H. Snieder, M.R. Robinson, and M.C. Mills, 2017, Nature Human Behaviour, 1, 757–765. doi:10.1038/s41562-017-0195-1
  • Meta-GWAS Accuracy and Power (MetaGAP) calculator shows that hiding heritability is partially due to imperfect genetic correlations across studies. R. de Vlaming, A. Okbay, C.A. Rietveld, M. Johannesson, P.K.E. Magnusson, A.G. Uitterlinden, F.J.A. van Rooij, A. Hofman, P.J.F. Groenen, A.R. Thurik, and P.D. Koellinger, 2017, PLOS Genetics, 13, e1006495. doi:10.1371/journal.pgen.1006495
  • Genome-wide analysis identifies 12 loci influencing human reproductive behavior. N. Barban, R. Jansen, R. de Vlaming, A. Vaez, J.J. Mandemakers, F.C. Tropf, X. Shen, J.F. Wilson, D.I. Chasman, I.M. Nolte, V. Tragante, S.W. van der Laan, J.R.B. Perry, A. Kong, ... D.J. Benjamin, D. Cesarini, P.D. Koellinger, M. den Hoed, H. Snieder, M.C. Mills, 2016, Nature Genetics, 48, 1462–1472. doi:10.1038/ng.3698
  • Genetic variants linked to education predict longevity. R.E. Marioni, S.J. Ritchie, P.K. Joshi, S.P. Hagenaars, A. Okbay, K. Fischer, M.J. Adams, W.D. Hill, G. Davies, Social Science Genetic Association Consortium, ... T. Esko, D.J. Porteous, C.R. Gale, and I.J. Deary, 2016, Proc Natl Acad Sci USA, 113, 13366–13371. doi:10.1073/pnas.1605334113
  • Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses. A. Okbay, B.M.L. Baselmans, J.E. de Neve, P. Turley, M.G. Nivard, M.A. Fontana, S.F.W. Meddens, R.K. Linner, C.A. Rietveld, J. Derringer, J. Gratten, J.J. Lee, J.Z. Liu, R. de Vlaming, T.S. Ahluwalia, ... R.F. Krueger, J.P. Beauchamp, P.D. Koellinger, D.J. Benjamin, M. Bartels, D. Cesarini, 2016, Nature Genetics, 48, 624–633. doi:10.1038/ng.3552
  • Genome-wide association study identifies 74 loci associated with educational attainment. A. Okbay, J.P. Beauchamp, M.A. Fontana, J.J. Lee, T.H. Pers, C.A. Rietveld, P. Turley, G.B. Chen, V. Emilsson, S.F.W. Meddens, S. Oskarsson, J.K. Pickrell, K. Thom, P. Timshel, R. de Vlaming, A. Abdellaoui, ... P.M. Visscher, T. Esko, P.D. Koellinger, D. Cesarini, D.J. Benjamin, 2016, Nature, 533, 539–542. doi:10.1038/nature17671
  • The Current and Future Use of Ridge Regression for Prediction in Quantitative Genetics. R. de Vlaming and P.J.F. Groenen, 2015, BioMed Research International, 2015, 143712. doi:10.1155/2015/143712

Preprint

  • Genomic SEM Provides Insights into the Multivariate Genetic Architecture of Complex Traits. A.D. Grotzinger, M. Rhemtulla, R. de Vlaming, S.J. Ritchie, T.T. Mallard, W.D. Hill, H.F. Ip, A.M. McIntosh, I.J. Deary, P.D. Koellinger, K.P. Harden, M.G. Nivard, and E.M. Tucker-Drob, 2018, bioRxiv, 305029. doi.org/10.1101/305029
  • Genome-wide study identifies 611 loci associated with risk tolerance and risky behaviors. R.K. Linnér, P. Biroli, E. Kong, S.F.W. Meddens, R. Wedow, M.A. Fontana, M. Lebreton, A. Abdellaoui, A.R. Hammerschlag, M.G. Nivard, A. Okbay, C.A. Rietveld, P.N. Timshel, S.P. Tino, M. Trzaskowski, R. de Vlaming, C.L. Zünd, Y. Bao, ..., J. Gratten, J.J. Lee, D.A. Cesarini, D.J. Benjamin, P.D. Koellinger, and J.P. Beauchamp, 2018, bioRxiv, 261081. doi.org/10.1101/261081
  • Genome-wide association study results for educational attainment aid in identifying genetic heterogeneity of schizophrenia. V. Bansal, M. Mitjans, C.A.P. Burik, R.K. Linnér, A. Okbay, C.A. Rietveld, M. Begemann, S. Bonn, S. Ripke, R. de Vlaming, M.G. Nivard, H. Ehrenreich, and P.D. Koellinger, 2018, bioRxiv, 114405. doi.org/10.1101/114405
  • Equivalence of LD-Score Regression and Individual-Level-Data Methods. R. de Vlaming, M. Johannesson, Patrik K.E. Magnusson, M. Arfan Ikram, and Peter M. Visscher, 2017, bioRxiv, 211821. doi.org/10.1101/211821

Books